Paaby lab

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Long, L., W. Xu, A.B. Paaby and P.T. McGrath. 2022. A toxin-antidote selfish element increases fitness of its host. bioRxiv.

Chou, H.T., F. Valencia, J.C. Alexander, A.D. Bell, D. Deb, D.A. Pollard and A.B. Paaby. 2022. Diversification of small RNA pathways underlies germline RNAi incompetence in wild C. elegans strains. bioRxiv.


Sloat, S.A, L.M. Noble, A.B. Paaby, M. Bernstein, A. Chang, T. Kaur, J. Yuen, S.C. Tintori, J.L. Jackson, A. Martel, J.A. Salome Correa, L. Stevens, K. Kionte, M. Blaxter and M.V. Rockman. 2022. Caenorhabditis nematodes colonize ephemeral resource patches in neotropical forests. Ecology and Evolution 12:e9124.

Kaul, S., H.T. Chou, S. Charles, G. Aubry, H. Lu and A.B. Paaby. 2022. Single-molecule FISH in C. elegans embryos reveals early embryonic expression dynamics of par-2, lgl-1 and chin-1 and possible differences between hyper-diverged strains. microPublication BIOLOGY 10.17912/micropub.biology.000609.

Charles, S., G. Aubry, H.T. Chou, A.B. Paaby and H. Lu. 2021. High-temporal-resolution smFISH method for gene expression studies in Caenorhabditis elegans embryos. Analytical Chemistry 93(3): 1369-1376.

Geiler-Samerotte, K.A., S. Li, C. Lazaris, A. Taylor, N. Ziv, C. Ramjeawan, A.B. Paaby and M.L. Siegal. 2020. Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping. PLOS Biology 18(8): e3000836.

Testa, N.D., S. Kaul, K.N. Le, M. Zhan, H. Lu and A.B. Paaby. 2020. A portable, low-cost device for precise control of specimen temperature under stereomicroscopes. PLOS ONE 15(3): e0230241.

Campbell, R.F., P.T. McGrath and A.B. Paaby. 2018. Analysis of epistasis in natural traits using model organisms. Trends in Genetics 34(11): 883-898.

Paaby, A.B. and N.D. Testa. 2018. Developmental Plasticity and Evolution. In: Nuno de la Rosa L., Müller G. (eds) Evolutionary Developmental Biology. Springer, Cham.

Paaby, A.B. and G. Gibson. 2016. Beyond the modern evolutionary synthesis: Cryptic genetic variation in evolutionary developmental genetics. MDPI Biology 5(28) doi:10.3390/biology5020028.

Paaby, A.B. , A.G. White, D.D. Riccardi, K.C. Gunsalus, F. Piano and M.V. Rockman. 2015. Wild worm embryogenesis harbors ubiquitous polygenic modifier variation. eLife 10.7554/eLife.09178.

Paaby, A.B. , A.O. Bergland, E.L. Behrman and P.S. Schmidt. 2014. A highly pleiotropic amino acid polymorphism in the Drosophila insulin receptor contributes to life history adaptation. Evolution 68(12): 3395-3409.

Paaby, A.B. and M.V. Rockman. 2014. Cryptic genetic variation: evolution’s hidden substrate. Nature Reviews Genetics 15(4): 247-258.

White, A.G., B. Lees, H.L. Kao, P.G. Cipriani, E. Munarriz, A.B. Paaby, K. Erickson, S. Guzman, K. Rattanakorn, E. Sontag, D. Geiger, K.C. Gunsalus, F. Piano. 2013. DevStaR: High-throughput quantification of C. elegans developmental stages. IEEE Transactions on Medical Imaging 32(10): 1791-1803.

Paaby, A.B. and M.V. Rockman. 2013. The many faces of pleiotropy. Trends in Genetics 29(2): 66-73.

  • Zhang, J. and G.P. Wagner. 2013. On the definition and measurement of pleiotropy. Trends in Genetics 29(7): 383-384.
  • Paaby, A.B. and M.V. Rockman. Pleiotropy: what do you mean? Reply to Zhang and Wagner. 2013. Trends in Genetics 29(7): 384.

Paaby, A.B. , M.J. Blacket, A.A. Hoffmann and P.S. Schmidt. 2010. Identification of a candidate adaptive polymorphism for Drosophila life history by parallel independent clines on two continents. Molecular Ecology 19(4): 760-774.

Paaby, A.B. and P.S. Schmidt. 2009. Dissecting the genetics of longevity in Drosophila melanogaster. Fly 3(1): 29-38.

Schmidt, P.S. and A.B. Paaby. 2008. Reproductive diapause and life history clines in North American populations of Drosophila melanogaster. Evolution 62(5): 1204-1215.

Paaby, A.B.  and P.S. Schmidt. 2008. Functional significance of allelic variation at methuselah, an aging gene in Drosophila. PLOS One 3(4): e1987.

Schmidt, P.S., A.B. Paaby and M.S. Heschel. 2005. Genetic variance for diapause expression and associated life histories in Drosophila melanogaster. Evolution 59(12): 2616-2625.

Walters, J.P., C.X. Muñoz, A.B. Paaby and S. DiNardo. 2005. Serrate-Notch signaling defines the scope of the initial denticle field by modulating EGFR activation. Developmental Biology 286: 415-426.