Paaby lab

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Publications

Long, L., W. Xu, A.B. Paaby and P.T. McGrath. 2023. A toxin-antidote selfish element increases fitness of its host. Elife 10.7554/eLife.81640.

Chou, H.T., F. Valencia, J.C. Alexander, A.D. Bell, D. Deb, D.A. Pollard and A.B. Paaby. 2023. Diversification of small RNA pathways underlies germline RNAi incompetence in wild C. elegans strains. Genetics: iyad191.

Bell, A.D., H.T. Chou and A.B. Paaby. 2023. Beyond the reference: gene expression variation and transcriptional response to RNA interference in Caenorhabditis elegans. G3 Genes|Genomes|Genetics 13(8):jkad112.

Sloat, S.A, L.M. Noble, A.B. Paaby, M. Bernstein, A. Chang, T. Kaur, J. Yuen, S.C. Tintori, J.L. Jackson, A. Martel, J.A. Salome Correa, L. Stevens, K. Kionte, M. Blaxter and M.V. Rockman. 2022. Caenorhabditis nematodes colonize ephemeral resource patches in neotropical forests. Ecology and Evolution 12:e9124.

Kaul, S., H.T. Chou, S. Charles, G. Aubry, H. Lu and A.B. Paaby. 2022. Single-molecule FISH in C. elegans embryos reveals early embryonic expression dynamics of par-2, lgl-1 and chin-1 and possible differences between hyper-diverged strains. microPublication BIOLOGY 10.17912/micropub.biology.000609.

Charles, S., G. Aubry, H.T. Chou, A.B. Paaby and H. Lu. 2021. High-temporal-resolution smFISH method for gene expression studies in Caenorhabditis elegans embryos. Analytical Chemistry 93(3): 1369-1376.

Geiler-Samerotte, K.A., S. Li, C. Lazaris, A. Taylor, N. Ziv, C. Ramjeawan, A.B. Paaby and M.L. Siegal. 2020. Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping. PLOS Biology 18(8): e3000836.

Testa, N.D., S. Kaul, K.N. Le, M. Zhan, H. Lu and A.B. Paaby. 2020. A portable, low-cost device for precise control of specimen temperature under stereomicroscopes. PLOS ONE 15(3): e0230241.

Campbell, R.F., P.T. McGrath and A.B. Paaby. 2018. Analysis of epistasis in natural traits using model organisms. Trends in Genetics 34(11): 883-898.

Paaby, A.B. and N.D. Testa. 2018. Developmental Plasticity and Evolution. In: Nuno de la Rosa L., Müller G. (eds) Evolutionary Developmental Biology. Springer, Cham.

Paaby, A.B. and G. Gibson. 2016. Beyond the modern evolutionary synthesis: Cryptic genetic variation in evolutionary developmental genetics. MDPI Biology 5(28) doi:10.3390/biology5020028.

Paaby, A.B. , A.G. White, D.D. Riccardi, K.C. Gunsalus, F. Piano and M.V. Rockman. 2015. Wild worm embryogenesis harbors ubiquitous polygenic modifier variation. eLife 10.7554/eLife.09178.

Paaby, A.B. , A.O. Bergland, E.L. Behrman and P.S. Schmidt. 2014. A highly pleiotropic amino acid polymorphism in the Drosophila insulin receptor contributes to life history adaptation. Evolution 68(12): 3395-3409.

Paaby, A.B. and M.V. Rockman. 2014. Cryptic genetic variation: evolution’s hidden substrate. Nature Reviews Genetics 15(4): 247-258.

White, A.G., B. Lees, H.L. Kao, P.G. Cipriani, E. Munarriz, A.B. Paaby, K. Erickson, S. Guzman, K. Rattanakorn, E. Sontag, D. Geiger, K.C. Gunsalus, F. Piano. 2013. DevStaR: High-throughput quantification of C. elegans developmental stages. IEEE Transactions on Medical Imaging 32(10): 1791-1803.

Paaby, A.B. and M.V. Rockman. 2013. The many faces of pleiotropy. Trends in Genetics 29(2): 66-73.

  • Zhang, J. and G.P. Wagner. 2013. On the definition and measurement of pleiotropy. Trends in Genetics 29(7): 383-384.
  • Paaby, A.B. and M.V. Rockman. Pleiotropy: what do you mean? Reply to Zhang and Wagner. 2013. Trends in Genetics 29(7): 384.

Paaby, A.B. , M.J. Blacket, A.A. Hoffmann and P.S. Schmidt. 2010. Identification of a candidate adaptive polymorphism for Drosophila life history by parallel independent clines on two continents. Molecular Ecology 19(4): 760-774.

Paaby, A.B. and P.S. Schmidt. 2009. Dissecting the genetics of longevity in Drosophila melanogaster. Fly 3(1): 29-38.

Schmidt, P.S. and A.B. Paaby. 2008. Reproductive diapause and life history clines in North American populations of Drosophila melanogaster. Evolution 62(5): 1204-1215.

Paaby, A.B.  and P.S. Schmidt. 2008. Functional significance of allelic variation at methuselah, an aging gene in Drosophila. PLOS One 3(4): e1987.

Schmidt, P.S., A.B. Paaby and M.S. Heschel. 2005. Genetic variance for diapause expression and associated life histories in Drosophila melanogaster. Evolution 59(12): 2616-2625.

Walters, J.P., C.X. Muñoz, A.B. Paaby and S. DiNardo. 2005. Serrate-Notch signaling defines the scope of the initial denticle field by modulating EGFR activation. Developmental Biology 286: 415-426.